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L'Oreal's 'Pill for Grey Hair' Raises Concerns!

When news broke this week that L'Oreal was developing a pill to prevent grey hair, it made headlines around the world. But scientists say the pill, which has not yet been created, produces more questions than answers. Bruno Bernard, head of the Hair Care, Quality and Color team at L'Oreal, first spoke about the cosmetic company's research, telling the Daily Mail the pill will be based on a fruit extract that mimics an enzyme called TRP-2, which isn't present in hair follicles. TRP-2 helps make pigment-producing cells called melanocytes.

In theory, the presence of TRP-2 could prevent hair from going gray. "Ideally you would take [the pill] for your whole life, but realistically we'd encourage people to start using it before their hair goes grey because we don't think it can reverse the process once it has started," he told the UK paper. "We have a watertight proof of concept, and we think it will have a market among men as well as women." Dr. Jonathan Zippin, a dermatologist at New York Presbyterian/Weill Cornell Medical Center, told ABCNews.com this kind of preventative solution to grey hair is "really difficult to prove" because some people never go grey, and others only grey a little bit. If researchers gave the pill to someone who never got grey hair, there would be no way to know if it was because of the pill or not.
In a statement released yesterday, L'Oreal briefly described its research efforts, but made no mention of a pill or the alleged 2015 release date widely reported by several media outlets. "L'Oreal has demonstrated and published in peer-reviewed journals the protective role of the enzyme TRP-2. Its absence in hair follicle melanocytes is likely linked to progressive greying," the statement reads. "Experts in the field confirm that substances mimicking TRP-2 activity might be of value to fight hair greying." But at this point, reports of a pill to prevent grey hair seem "a little premature," according to L'Oreal spokesman Jonathan Maher.

"We're still very much in the research phase," he said, adding that he cannot go into further detail. Scientists at the Ito Lab at New York University's Langone Medical Center are also researching grey hair, and recently identified the proteins responsible for pigment. In June they published a paper in the journal Cell, announcing that a network of proteins called the wnt signaling pathway are responsible for preventing grey hair in mice.

"Mouse and the human hairs are very similar in the way that they are structured and the way they contain melanocyte stem cells. We found that the wnt signaling pathway is activated the same way," said Piul Rabbani, a grad student in NYU's Langone Medical Center who led the study, told ABC News in June.

Low iron diet cuts brain disease risk!

Just the right amount of iron is needed for proper cell functioning but an excess could trigger brain diseases like Alzheimer`s and Parkinson`s, new research says.

Men have more iron in their system than women, which may explain why they develop these age-related degenerative diseases at a younger age.

Women lose iron through blood loss during menstruation, so a lesser number of them have these diseases, according to a University of California, Los Angeles (UCLA) study, the journal Neurobiology of Aging reports.

George Bartzokis, professor of psychiatry at the UCLA and colleagues compared iron levels in women who had their uterus removed (hysterectomy) before menopause and thus did not menstruate and lose iron, with levels in postmenopausal women who had not gone through the procedure.

They found the women who had undergone hysterectomy had higher levels of iron in their brains than the women who hadn`t, compared to that of the men, according to a UCLA statement.

"But there are things postmenopausal women and especially men can do to reduce their iron levels through relatively simple actions," Bartzokis said.

"These include not overloading themselves with over-the-counter supplements that contain iron, unless recommended by their doctor; eating less red meat, which contains high levels of iron; donating blood; (taking) curcumin or green tea, that may have positive health consequences," Bartzokis said.

Researchers used an MRI technique that can measure the amount of ferritin iron in the brain (ferritin is a protein that stores iron).

They examined 39 postmenopausal women, 15 of whom had undergone a hysterectomy. They looked at three white-matter and and five gray-matter regions of the brain. Fifty-four male subjects were also imaged for comparison.

The researchers found that 15 of the women who had hysterectomy had concentrations of iron in the brain`s white-matter regions that did not differ from the men`s levels.

Further, both the women who had a hysterectomy and the men, had significantly higher amounts of iron than the women who had not undergone a hysterectomy.

Genelia D'Souza engaged to Riteish Deshmukh!

In a hush hush ceremony, Genelia D’Souza engaged to Riteish Deshmukh at Riteish Deshmukh's father, Maharashtra CM Vilasrao Deshmukh's residence a fortnight ago. It was a complete private affair and no personalities from the film industry were invited. The ceremony took place in the attendance of close family members and friends. The exact date of their marriage has not yet been revealed. Genelia and Riteish have been dating for almost seven years but the couple always avoids talking about their relationship in public. The duo is very much confirmed about settling down but they took time to convince their family as the actor’s family wanted Riteish to marry a girl from their community.

Master of the sky!

The C-130 J has been designed and developed with mission flexibility in mind - combat delivery, air to air refueling, special operations, disaster relief and humanitarian missions, that gives the C-130 J a unique mix of agility and performance to consistently operate at very high tempo operations efficiently as seen in the recent Sikkim earthquakes.The icing on the cake for Indian pilots who are going to navigate these mighty machines in the skies - a microwave oven, a coffee dispenser and bunks to catch up on sleep - cockpits seem a much better place for Indian Air Force (IAF) transport pilots.

India has purchased 6 C-130J-30 aircraft from the Government of United States of America (USG) through the Foreign Military Sales (FMS) route at a cost of US $ 962 million which includes the cost on account of training, role and support equipment, spares, warranty and US Government administrative charges.

Equipped with India-unique operational equipment, including an infrared detection set (IDS), the aircraft for the first time will provide the IAF an ability to conduct precision low-level flying operations, airdrops and landings in blackout conditions.

The C-130J Super Hercules is the only airlifter with the range and flexibility for emerging theaters and evolving concepts of operation. This tactical transport aircraft has already proven itself in many kinds of missions, many in the harshest operating conditions possible.

The C-130J is an all-new aircraft. Major improvements include a state-of-the-art, computer-controlled digital flight deck designed for two-pilot operation and equipped with twin mission computers.

The aircraft can also be configured with the "enhanced cargo handling system". The system consists of a computerised loadmaster's station from where the user can remotely control the under floor winch.

The aircraft is equipped with air-to-air receiver refueling capability for extended range operations. Lockheed Martin will integrate this equipment and other capabilities into the Indian configuration as agreed between the governments.

Everest faces rocky future as ice melts!

Climbers and custodians of Everest say rapid climate change could soon make for an ice-free ascent of the world's highest mountain.

Their warning comes amid a new international effort to gauge the effects of climate change in the Himalayas - and shield local people from potential hazards.

A US-funded mission, led by the Mountain Institute, opened a meeting in Kathmandu at the weekend aimed at finding practical solutions to the threat of catastrophic high-altitude flooding from lakes forming at the foot of melting glaciers.

Anecdotal evidence suggests the climbing experience is now far different from that Sir Edmund Hillary and Tenzing Norgay faced in 1953. However, scientists acknowledge they have yet to form a complete picture of the changes under way in the Himalayas.

The task of offering a definitive scientific account of the extent of melting is daunting - and not just because the area is so vast and inaccessible.

Scientists are still working to recover from a PR disaster early last year when it emerged that a United Nations report on climate change had claimed - wrongly - that the Himalayan glaciers would disappear by 2035.

But growing anecdotal evidence from climbers and local people suggests climate change is making a strong impact even well above the 8000m line, with signs of melting ice on the southern approach to Everest.

"When I climbed Mt Everest last year I climbed the majority of ice without crampons because there was so much bare rock," said John All, an expert on Nepal glaciers from the University of Western Kentucky.

"In the past that would have been suicide because there was so much ice."

He said the terrain he crossed was very different from the landscapes described by earlier generations of climbers. Historical photographs of the Everest region show a longer and deeper covering of ice.

All added: "I wonder when Mt Everest will finally become a rock climb rather than an ice climb."

Everest Base Camp has undergone similar changes, said Tshering Tenzing Sherpa, who has overseen rubbish collection at the site for the past few years.

The summer monsoon months brought several deep new crevasses in the black ice beneath the rocks, Tenzing said. "Everything is changing with the glaciers."

Mancini knows Munich milestone!

Manchester City will reach the latest stage of their remarkable journey in Munich on Tuesday night with manager Roberto Mancini insisting one game alone against the legendary Bayern "cannot change" a club.Since Sheikh Mansour completed his multi-million pound Blues buy-out in 2008, City's long-suffering fans have become numb such is the frequency with which they have had to pinch themselves.From the day it all began and that British record £32.5million purchase of Robinho, through the arrival of Carlos Tevez from Manchester United, last season's FA Cup triumph and top-three finish, City have hauled in the heavyweights above them.

"For the supporters it is an important moment," Mancini said.Now, with so much less distance to travel, the strides are shorter. Some are still very significant.When they walk out at the Allianz Arena to face a team that were Champions League runners-up as recently as 2010, knocking Manchester United out along the way, and have four European Cups in their trophy room bearing testament to their status in the game, for those who have loyally followed the Blues through decades of underachievement another marker will have been passed.Mancini added: "Life changes sometimes.

Now we are a top club. But one result or one game cannot change everything. As a club, a team and a squad we have improved a lot this year and hope to do so in the future. But it is clear that it is an important game for this group. If we win it will be very important."That a club who only 13 years ago were spending their midweeks dreaming of victory over Macclesfield are now taking on Bayern as equals is remarkable in itself. Yet a quick check through the names who might represent the Blues in Germany emphasises Mancini and his boys are not travelling to Bavaria to gaze around at a world-famous stadium and wonder in amazement at it all.

Sergio Aguero, Yaya Toure, David Silva, Joe Hart. This City squad stands comparison with any potential foe in this competition, including a Bayern outfit who can boast Arjen Robben, Franck Ribery and Manuel Neuer in its ranks."Playing against Bayern Munich is always difficult for an English team. But the same is also (true) for them," said Mancini."It will be a difficult game. When you play against this team you can lose. But we are not a small team. We are a good team. We play against them without a problem. We have a lot of respect for them. They have a great history. But we want to do a good job."