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L'Oreal's 'Pill for Grey Hair' Raises Concerns!

When news broke this week that L'Oreal was developing a pill to prevent grey hair, it made headlines around the world. But scientists say the pill, which has not yet been created, produces more questions than answers. Bruno Bernard, head of the Hair Care, Quality and Color team at L'Oreal, first spoke about the cosmetic company's research, telling the Daily Mail the pill will be based on a fruit extract that mimics an enzyme called TRP-2, which isn't present in hair follicles. TRP-2 helps make pigment-producing cells called melanocytes.

In theory, the presence of TRP-2 could prevent hair from going gray. "Ideally you would take [the pill] for your whole life, but realistically we'd encourage people to start using it before their hair goes grey because we don't think it can reverse the process once it has started," he told the UK paper. "We have a watertight proof of concept, and we think it will have a market among men as well as women." Dr. Jonathan Zippin, a dermatologist at New York Presbyterian/Weill Cornell Medical Center, told ABCNews.com this kind of preventative solution to grey hair is "really difficult to prove" because some people never go grey, and others only grey a little bit. If researchers gave the pill to someone who never got grey hair, there would be no way to know if it was because of the pill or not.
In a statement released yesterday, L'Oreal briefly described its research efforts, but made no mention of a pill or the alleged 2015 release date widely reported by several media outlets. "L'Oreal has demonstrated and published in peer-reviewed journals the protective role of the enzyme TRP-2. Its absence in hair follicle melanocytes is likely linked to progressive greying," the statement reads. "Experts in the field confirm that substances mimicking TRP-2 activity might be of value to fight hair greying." But at this point, reports of a pill to prevent grey hair seem "a little premature," according to L'Oreal spokesman Jonathan Maher.

"We're still very much in the research phase," he said, adding that he cannot go into further detail. Scientists at the Ito Lab at New York University's Langone Medical Center are also researching grey hair, and recently identified the proteins responsible for pigment. In June they published a paper in the journal Cell, announcing that a network of proteins called the wnt signaling pathway are responsible for preventing grey hair in mice.

"Mouse and the human hairs are very similar in the way that they are structured and the way they contain melanocyte stem cells. We found that the wnt signaling pathway is activated the same way," said Piul Rabbani, a grad student in NYU's Langone Medical Center who led the study, told ABC News in June.

Low iron diet cuts brain disease risk!

Just the right amount of iron is needed for proper cell functioning but an excess could trigger brain diseases like Alzheimer`s and Parkinson`s, new research says.

Men have more iron in their system than women, which may explain why they develop these age-related degenerative diseases at a younger age.

Women lose iron through blood loss during menstruation, so a lesser number of them have these diseases, according to a University of California, Los Angeles (UCLA) study, the journal Neurobiology of Aging reports.

George Bartzokis, professor of psychiatry at the UCLA and colleagues compared iron levels in women who had their uterus removed (hysterectomy) before menopause and thus did not menstruate and lose iron, with levels in postmenopausal women who had not gone through the procedure.

They found the women who had undergone hysterectomy had higher levels of iron in their brains than the women who hadn`t, compared to that of the men, according to a UCLA statement.

"But there are things postmenopausal women and especially men can do to reduce their iron levels through relatively simple actions," Bartzokis said.

"These include not overloading themselves with over-the-counter supplements that contain iron, unless recommended by their doctor; eating less red meat, which contains high levels of iron; donating blood; (taking) curcumin or green tea, that may have positive health consequences," Bartzokis said.

Researchers used an MRI technique that can measure the amount of ferritin iron in the brain (ferritin is a protein that stores iron).

They examined 39 postmenopausal women, 15 of whom had undergone a hysterectomy. They looked at three white-matter and and five gray-matter regions of the brain. Fifty-four male subjects were also imaged for comparison.

The researchers found that 15 of the women who had hysterectomy had concentrations of iron in the brain`s white-matter regions that did not differ from the men`s levels.

Further, both the women who had a hysterectomy and the men, had significantly higher amounts of iron than the women who had not undergone a hysterectomy.

Genelia D'Souza engaged to Riteish Deshmukh!

In a hush hush ceremony, Genelia D’Souza engaged to Riteish Deshmukh at Riteish Deshmukh's father, Maharashtra CM Vilasrao Deshmukh's residence a fortnight ago. It was a complete private affair and no personalities from the film industry were invited. The ceremony took place in the attendance of close family members and friends. The exact date of their marriage has not yet been revealed. Genelia and Riteish have been dating for almost seven years but the couple always avoids talking about their relationship in public. The duo is very much confirmed about settling down but they took time to convince their family as the actor’s family wanted Riteish to marry a girl from their community.